New Leaf Venture Partners, L.L.C 13F annual report

New Leaf Venture Partners, L.L.C is an investment fund managing more than $116 billion ran by Craig Slutzkin. There are currently 14 companies in Mr. Slutzkin’s portfolio. The largest investments include Arvinas Inc and Rallybio Corporation, together worth $50.7 billion.

$116 billion Assets Under Management (AUM)

As of 3rd August 2023, New Leaf Venture Partners, L.L.C’s top holding is 1,289,521 shares of Arvinas Inc currently worth over $32 billion and making up 27.5% of the portfolio value. Relative to the number of outstanding shares of Arvinas Inc, New Leaf Venture Partners, L.L.C owns more than approximately 0.1% of the company. In addition, the fund holds 3,301,603 shares of Rallybio Corporation worth $18.7 billion. The third-largest holding is Dice Therapeutics Inc worth $17.3 billion and the next is Deciphera Pharmaceuticals Inc worth $17 billion, with 1,209,571 shares owned.

Currently, New Leaf Venture Partners, L.L.C's portfolio is worth at least $116 billion. The total portfolio value may be much higher due to cash assets that are not publicly disclosed such as fixed income, real estate, or cash equivalents.

Careers at New Leaf Venture Partners, L.L.C

The New Leaf Venture Partners, L.L.C office and employees reside in New York, New York. According to the last 13-F report filed with the SEC, Craig Slutzkin serves as the Chief Financial Officer at New Leaf Venture Partners, L.L.C.

Recent trades

In the most recent 13F filing, New Leaf Venture Partners, L.L.C revealed that it had opened a new position in Rocket Pharmaceuticals Inc and bought 118,242 shares worth $2.35 billion. This means they effectively own approximately 0.1% of the company. Rocket Pharmaceuticals Inc makes up 3.4% of the fund's Health Care sector allocation and has grown its share price by 0.3% in the past year.

The investment fund also strengthened its position in Rallybio Corporation by buying 1,000,000 additional shares. This makes their stake in Rallybio Corporation total 3,301,603 shares worth $18.7 billion.

On the other hand, there are companies that New Leaf Venture Partners, L.L.C is getting rid of from its portfolio. New Leaf Venture Partners, L.L.C closed its position in Sierra Oncology Inc on 10th August 2023. It sold the previously owned 219,251 shares for $12.1 million. Craig Slutzkin also disclosed a decreased stake in Dice Therapeutics Inc by 0.3%. This leaves the value of the investment at $17.3 billion and 371,693 shares.

One of the smallest hedge funds

The two most similar investment funds to New Leaf Venture Partners, L.L.C are Disciplined Equity Management and Geneva Partners. They manage $116 billion and $116 billion respectively.


Craig Slutzkin investment strategy

New Leaf Venture Partners, L.L.C’s portfolio is diversified across 2 sectors. Currently, their heaviest sector is Health Care — making up 58.8% of the total portfolio value. The fund focuses on investments in the United States as 71.4% of the portfolio companies are based in the United States.

The majority of the companies in the fund’s portfolio are small-cap stocks. Stocks with a size of more than $100 million in market cap make up 21% of the total holdings value. On the other hand, large-cap stocks make up only approximately 0.1% of the portfolio. The average market cap of the portfolio companies is close to $691 million.

The complete list of New Leaf Venture Partners, L.L.C trades based on 13F SEC filings

These positions were updated on August 10th based on the fund’s latest 13F filing. Quickly find out what the most recently closed or increased positions are.

Security Shares Owned Value Allocation
Arvinas Inc
No change
1,289,521
$32,005,911,000 27.49%
Rallybio Corporation
43.45%
3,301,603
$18,687,073,000 16.05%
Dice Therapeutics Inc
33.23%
371,693
$17,268,857,000 14.83%
Deciphera Pharmaceuticals Inc
No change
1,209,571
$17,030,760,000 14.63%
Edgewise Therapeutics Inc
No change
1,553,661
$12,040,873,000 10.34%
Cogent Biosciences, Inc.
No change
501,530
$5,938,115,000 5.10%
Crinetics Pharmaceuticals Inc
No change
141,000
$2,540,820,000 2.18%
Rocket Pharmaceuticals Inc
Opened
118,242
$2,349,469,000 2.02%
Passage Bio Inc
No change
2,497,922
$2,348,047,000 2.02%
Harpoon Therapeutics, Inc.
No change
3,156,699
$2,241,256,000 1.92%
Alector, Inc.
No change
339,569
$2,040,810,000 1.75%
Aravive Inc
No change
946,423
$1,192,493,000 1.02%
X4 Pharmaceuticals, Inc.
No change
335,000
$649,900,000 0.56%
Iterum Therapeutics Plc
Opened
97,084
$103,880,000 0.09%
Sierra Oncology Inc
Closed
219,251
$12,057,000
Amryt Pharma plc
Closed
449,737
$3,144,000
Chimerix Inc
Closed
1,224,600
$2,547,000
Aptinyx Inc
Closed
3,290,079
$1,836,000
Renovacor Corporation
Closed
670,689
$1,360,000
PDS Biotechnology Corporation
Closed
117,242
$428,000
Iterum Therapeutics Plc
Closed
1,456,303
$292,000
AvroBio Inc
Closed
315,550
$290,000
Addex Therapeutics Ltd
Closed
50,000
$58,000
No transactions found
Showing first 500 out of 23 holdings